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Novartis has reported topline data from P-III (REMODEL-1/-2) trials assessing remibrutinib (100mg) vs teriflunomide in ~2,000 adults with relapsing multiple sclerosis (RMS)
Remibrutinib met the 1EP, significantly reducing annualized relapse rate (ARR), plus trial showed clinically meaningful reductions in key 2EPs related to disability progression, with a positive trend in 3mCDP & nominally significant improvement in 6mCDP in the preplanned combined analysis; data to be presented at MSToronto2026
Remibrutinib is a highly selective, potent oral BTK inhibitor, with Novartis planning to seek global regulatory approval for its use in RMS
Ref: Globenewswire | Image: Novartis | Press Release
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The post Novartis Reports P-III (REMODEL-1/-2) Trial Data on Remibrutinib for Relapsing Multiple Sclerosis appeared first on PharmaShots.
Novartis Reports P-III (REMODEL-1/-2) Trial Data on Remibrutinib for Relapsing Multiple Sclerosis | PharmaVoice