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The NMPA has granted conditional approval to Orpathys for the treatment of LA/M gastric cancer or gastroesophageal junction (GC/GEJ) adenocarcinoma pts with MET amplification who have failed ≥2 prior systemic treatments
Approval was supported by the P-II trial of Orpathys in GC/GEJ adenocarcinoma pts with MET amplification in China, which showed 32.3% ORR (1EP), & improved 2EPs, incl. 63.1% DCR, 1.4mos. mTTR, 9.7mos. mDoR, & 4mos. mPFS (as per Oct 8, 2025); data were published in Nature Medicine
Orpathys (PO) is a MET tyrosine kinase inhibitor co-developed by AstraZeneca and HUTCHMED and is being commercialized by AstraZeneca
Ref: Globenewswire | Image: HUTCHMED | Press Release
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The post HUTCHMED Reports NMPA Conditional Approval of Orpathys (Savolitinib) for Gastric Cancer Patients with MET Amplification appeared first on PharmaShots.
HUTCHMED Reports NMPA Conditional Approval of Orpathys (Savolitinib) for Gastric Cancer Patients with MET Amplification | PharmaVoice